E-mail: Yip, Albert S.C. Chan.

with the reproduced material. The Mannich reaction has been widely used to effectively construct C–N and C–C bonds in organic synthesis.

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Reproduced material should be attributed as follows: If the material has been adapted instead of reproduced from the original RSC publication 7H2O as an Efficient Catalyst for One-Pot Synthesis of Highly Functionalized Piperidines via Multi-component Organic Reactions.

Christian Gnamm, Caroline M. Krauter, Kerstin Brödner, Günter Helmchen.

is available on our Permission Requests page. Franklin A Davis, Jianghe Deng, Yulian Zhang, R.Curtis Haltiwanger. Information about reproducing material from RSC articles with different licences Manas K. Ghorai, Amit Kumar, Sandipan Halder.

Chun-Ling Gu, Li Liu, Dong Wang, Yong-Jun Chen.

Synthesis of polysubstituted pyrroles from sulfinimines (N-sulfinyl imines). Franklin A. Davis, Bin Chao, Ashwin Rao. The reaction is named after chemist Carl Mannich.
Chapter 6.1 Six-membered ring systems: Pyridines and benzo derivatives. "Reproduced from" can be substituted with "Adapted from".

Christian Gnamm, Kerstin Brödner, Caroline M. Krauter, Günter Helmchen. If you are the author of this article you still need to obtain permission to reproduce

Proline-Catalyzed Imino-Diels–Alder Reactions: Synthesis ofmeso-2,6-Diaryl-4-piperidones. Please reconnect. Xiao-Dong Jia, Wen-Juan Wang, Cong-De Huo, Yan Ren, Xiang-Ning Chen, Xiao-Lan Xu, Xi-Cun Wang.

Abu T. Khan, Mohan Lal, Md. The Mannich reaction is an organic reaction which consists of an amino alkylation of an acidic proton placed next to a carbonyl functional group by formaldehyde and a primary or secondary amine or ammonia. This was produced by version 4.1 of GNU libplot, a free library for exporting 2-D vector graphics. Li-Chun Feng, Ya-Wei Sun, Wei-Jun Tang, Li-Jin Xu, Kim-Lung Lam, Zhongyuan Zhou, Albert S. C. Chan.

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In all cases the Ref. N N

Reactions between aldimines and α-methylene carbonyls are also considered Mannich reactions because these imines form between amines and aldehydes.

-Aryl Substituted Piperidones. Sergio Pinheiro, Sandro J. Greco, Leandro S. Veiga, Florence M.C. Philip M. Weintraub, Jeffrey S. Sabol, John M. Kane, David R. Borcherding. Nicolas Gouault, Myriam Le Roch, Gisele de Campos Pinto, Michèle David. The enantioselective synthesis of poison-frog alkaloids (−)-203A, (−)-209B, (−)-231C, (−)-233D, and (−)-235B″.

: A recyclable catalyst for multicomponent coupling reaction for the efficient synthesis of functionalized piperidines. This review focuses on selected applications of the intramolecular Mannich reaction as a key step in the total synthesis of natural products (2000–2017).

Synthesis of highly functionalized piperidines by one-pot multicomponent reaction using tetrabutylammonium tribromide (TBATB). Monatshefte für Chemie - Chemical Monthly. XX is the XXth reference in the list of references. If the file has been modified from its original state, some details may not fully reflect the modified file.

Double Mannich Reaction and Tandem Cyclization of Imines with Ketones Catalyzed by Indium(III) Chloride Tetrahydrate: Stereoselective Synthesis of Highly Substituted 4-Piperidones. A new asymmetric synthesis of 2,6-cis-disubstituted 4-methylenepiperidines: total synthesis of (+)-alkaloid 241D and (+)-isosolenopsin A. C. Ramalingan, S. Balasubramanian, S. Kabilan. Highly diastereoselective addition of nitromethane anion to chiral α-amidoalkylphenyl sulfones. In summary, we have introduced a new type of intramolecular redox-Mannich reaction that is complementary to the classic Reinhoudt reaction in that it provides regioisomeric products differing only in the position of one methylene bridge.

Elisabetta Foresti, Gianni Palmieri, Marino Petrini, Roberto Profeta.

ChemInform Abstract: Intramolecular Mannich Reaction in the Asymmetric Synthesis of Polysubstituted Piperidines: Concise Synthesis of the Dendrobate Alkaloid (+)-241D (I) and Its C-4 Epimer (II).. Franklin A. Davis, Bin Chao, Yemane W. Andemichael, Pradyumna K. Mohanty, Tianan Fang, David M. Burns, Ashwin Rao, Joanna M. Szewczyk.

A New Method of Synthesis of 6-Substituted Piperidine-2,4-diones from Homoallylamines. Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, East China Normal University, 3663N Zhongshan Road, Shanghai 200062, China Stereoselective Mannich reaction of camphor titanium enolate.

Photodesulfinylation of optically active N-sulfinyl amines. The following pages on the English Wikipedia use this file (pages on other projects are not listed): (SVG file, nominally 252 × 90 pixels, file size: 23 KB).

First enantioselective synthesis of (+)-quinolizidine : determination of the absolute stereochemistry. Musawwer Khan, Kranthi K.R. A Facile Synthesis of

A Configurational Switch Based on Iridium-Catalyzed Allylic Cyclization: Application in Asymmetric Total Syntheses of Prosopis, Dendrobate, and Spruce Alkaloids.

Iodine catalyzed one-pot five-component reactions for direct synthesis of densely functionalized piperidines. de Farias, Paulo R.R. This review focuses on selected applications of the intramolecular Mannich reaction as a key step in the total synthesis of natural products (2000–2017). Seyed Sajad Sajadikhah, Malek Taher Maghsoodlou, Nourallah Hazeri, Sayyed Mostafa Habibi-Khorassani, Sayyed Jalal Shams-Najafi.

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contained in this article in third party publications C. Ramalingan, S. Balasubramanian, S. Kabilan, M. Vasudevan. Kuznetsov, Victor I. Maleev, Victor N. Khrustalev, Anna F. Mkrtchyan, Ivan A. Godovikov, Tatyana V. Strelkova, Yuri N. Bubnov.

or in a thesis or dissertation provided that the correct acknowledgement is given Stereoselective synthesis of dendrobate alkaloid (+)-241D and its C-4 epimer.

-Sulfinyl Imines).

This transformation enables rapid access to products containing the tetrahydroprotoberberine core.

The final product is a β-amino-carbonyl compound also known as a Mannich base. Synthesis and study of antibacterial and antifungal activities of novel 1-[2-(benzoxazol-2-yl)ethoxy]- 2,6-diarylpiperidin-4-ones.
qlwang@library.ecnu.edu.cn, c Nikolai Yu.

Recent advances in asymmetric reactions using sulfinimines (N-sulfinyl imines). Fernando Aznar, Ana-Belén García, María-Paz Cabal.

Asymmetric Synthesis Using Sulfinimines ( D. Scott Coffey, Stanley P. Kolis, Scott A.

Aziridine-mediated asymmetric synthesis of quaternary β-amino acids using 2H-azirine 2-carboxylate esters.

Franklin A. Davis, Kerisha A. Bowen, He Xu, Venkata Velvadapu. Asymmetric synthesis of (+)-preussin from N-sulfinyl δ-amino β-ketoesters. English: Intramolecular Mannich reaction - pyrrolizidine core synthesis Русский: Внутримолекулярная реакция Манниха при синтезе пирролизидинового ядра